25.09.2017 15:17 - About Us - Mediadaten - Imprint & Contact - succidia AG
Chromchat RSS

Does increased LC peak capacity equal increased value for complex sample analysis?

The meaning of peak capacity - von Dr Frank Steiner

Despite the strength of liquid chromatography (LC) to separate compounds through well tunable selective retention, its efficiency lags behind gas chromatography (GC) that can deliver up to several millions of plates per column. Resolution improvement in LC should thus be addressed with selectivity optimization first. If samples get too complex, however, this approach is no longer feasible, as improving selectivity in one part of the chromatogram will...

Clenbuterol testing in doping control samples: drug abuse or food contamination?

Meat as a Doping Trap - von Prof. Dr Mario Thevis, Prof. Dr Wilhelm Schänzer

Clenbuterol, a ß<sub>...

Clenbuterol testing in doping control samples: drug abuse or food contamination?

Meat as a doping trap - von Prof. Dr Mario Thevis, Prof. Dr Wilhelm Schänzer

Clenbuterol, a ß<sup>...

Pharmaceutical counterion determination

House lights down, stage lights up - von Dr Frank Steiner, Dr Carsten Paul, Dr Mark Tracy

In contemporary practice, roughly half of all active pharmaceutical ­ingredients (APIs) are administered as salts. The use of the protonated ­or deprotonated form of the drug substance combined with the selection of counterions enables the targeted variation of key parameters, such as solubility and stability. Analysis of the corresponding counterions constitutes an essential part of the development process for new pharmaceuticals and is now an...

Instrumental and effect-directed analysis in the oxidative degradation of micropollutants

Pharmaceuticals in wastewater - von Dr Jochen Türk

Occurance and fate of micropollutants, metabolites and transformation products in the water cycle is placing increasingly higher demands on instrumental analysis in terms of resolution and sensitivity. As yet, effect-directed analysis methods play a subordinate role in water analysis work. Yet for evaluating unknown samples or ingredients, these methods form a perfect complement to instrument-based identification. Indeed, in the detection of estrogenically...

More reproducible retention times

Best HPLC-Chromatograms - von Dr Andrea Junker-Buchheit

The high health hazard potential of many ­organic solvents is well known to anyone working in a laboratory. Solvent vapours ­can not only endanger people’s health, but also increase the fire and explosion risks for laboratories and buildings, in addition to causing air pollution. This is also the case for analytical and preparative HPLC laboratories.