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L&Mint-int-1-2015

Food safety as a global challenge

What makes something “authentic”? - von Prof. Dr Markus Fischer

Whether a foodstuff is “authentic” – i.e. whether it is genuine or original – is of considerable importance not only ­for the complex and global procurement chain that drives the food processing/­manufacturing industries but also for consumer safety.

Fractionation of functional peptides with ion-­exchange membrane adsorption chromatography

Separation via binding - von Prof. Dr Ulrich Kulozik, Elena Leeb

By deploying specific proteases for the enzymatic hydro­lysis of proteins, the release of peptides can be controlled. This process ­can be used to produce functional peptides, which may exhibit an ability to reduce blood pressure or have a surface-active function. The deployment of biofunctional peptides in food as an “added value” is only ­possible at sufficiently effective concentrations, ­however. Accordingly, processes are required that...

Image-based cytometry – a technology conquers cell culture

Star charts and Petri dishes - von Dr Daniel H. Rapoport, Dr Tim Becker

Cell cultivation has now become an indispensable part of scientific investigation and applications within medicine. From a simple substance test to the autologous cell therapies of the future, cell technologies are based on the controlled propagation of cells. An important step towards this goal is the non-invasive characterisation of the cell population grown. New methods in image-based cytometry offer an ideal platform technology for this purpose.

lab&more in conversation with Dr Stefan Lamotte, Research Scientist, Separation Science & Hyphenated Techniques, Competence Center Analytics, BASF SE

Wanted: Universal detectability - von Dr Stefan Lamotte

Analytical procedures in the laboratory span a variety of chromatographic techniques such as high performance liquid chromatography (HPLC), gas chromatography (GC), supercritical fluid chromatography (SFC) and capillary electrophoresis (CE). Samples analyzed in the laboratory by HPLC are often non-volatile and without a chromophor, thus common UV detectors are not suitable. Alternatively, more universal detectors, based on aerosol techniques such...

New High Purity Grade of Solvents for UHPLC-MS Instrumentation

Fisher Chemical Optima UHPLC-MS solvents designed to reduce background signal and increase sensitivity for rapid trace analysis

ST. LOUIS, Mo. – ASMS2015 – (June 1, 2015) – New, exceptionally pure mobile phase solvents for ultra-high-performance liquid chromatography–mass spectrometry (UHPLC-MS) instruments have been designed to reduce background signal and minimize chromatographic interferences, facilitating accurate, sensitive and rapid trace analysis.

New Tribrid Mass Spectrometer with Improved Sensitivity Redefines the Limits of Protein and Small Molecule Quantitation and Characterization

Delivering new levels of performance and usability for the most challenging research applications

ST. LOUIS, MO – ASMS Conference – (June 1, 2015) - Scientists performing advanced research in proteomics, biopharma, and metabolism/metabolomics can now test new limits of detection, characterization and quantitation with the latest tribrid mass spectrometer.

The critical role of fatty acid channeling between membrane and storage lipids

When lipid meta­bolism breaks down - von Prof. Dr Sepp D. Kohlwein, Dr Neha Chauhan, Dr Harald F. Hofbauer

Although as thin as the skin of a soap bubble, they are nonetheless vitally ­important. Biological membranes, 10,000 times thinner than a human hair, ­form a physiological barrier to all the cells in our body and are thus responsible for mediating exchanges between the cell interior and the external environment. Minor changes to their composition, such as those involved in lipid meta­bolism disorders, can have fatal consequences for events within...

The effects of psychotherapy on DNA damage caused by traumatic stress

Molecular consequences - von Dr Maria Moreno-Villanueva

The natural and social environment plays a decisive role in the life of an indivi­dual, and has significant repercussions for his or her physical and mental health. Factors in the social environment such as a high population density or noisy cities with traffic congestion and light pollution are considered to be ­potential stress factors. Social relationships and the working environment ­also exert a considerable influence on a person’s psyche...

L&M int. 1 / 2015

The articles are publishes in issue L&M int. 1 / 2015. Free download here: download here